FTO antibody,Genetex,GTX131517

Host

Rabbit

Reactivity

Human, Rat

Application

WB ICC/IF

Conjugate

Unconjugated

Platform ID

BAB093489570

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameFTO antibody
Cat. No.GTX131517
Gene ID (Entrez)79068
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF
ClonalityPolyclonal
Concentration2.05 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFTO
ImmunogenRecombinant protein encompassing a sequence within the center region of human FTO. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death. [provided by RefSeq]

Synonyms

FTO alpha-ketoglutarate dependent dioxygenase , ALKBH9 , BMIQ14 , GDFD

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