FTO antibody, N-term,Genetex,GTX81611

Host

Rabbit

Reactivity

Human

Application

WB IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB813345253

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFTO antibody, N-term
Cat. No.GTX81611
Gene ID (Entrez)79068
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P FCM
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetFTO
ImmunogenKLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FTO.
PurityProtein A purified, followed by peptide affinity purification.
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

Synonyms

FTO alpha-ketoglutarate dependent dioxygenase , ALKBH9 , BMIQ14 , GDFD

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