FUS2 antibody [AT2F4],Genetex,GTX50012

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF

Conjugate

Unconjugated

Platform ID

BAB303111432

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background

Specifications

NameFUS2 antibody [AT2F4]
Cat. No.GTX50012
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenRecombinant FUS2 (1-308aa) purified from E. coli
PurityBy protein-G affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Vertebrate FUS2 genes, which are known to be putative tumor suppressor gene, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain is essential enzymes involved in several sophisticated cellular processes such as N-acetylation, O-acetylatin. NAT enzymes may be involved in susceptibility to cancer including colorectal cancer because of the presence of carcinogenic heterocyclic amines in some cooked foods. FUS2 was physically localized to the cytoplasm. Also, FUS2 showed the actin dependent movement, closely related to the polarization in the budding yeast, Saccharomyces cerevisiae.

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