FZD7 Rabbit pAb- ABclonal,ABclonal,A4213
Reactivity
Human, Mouse
Application
WB, ELISA
Conjugate
Unconjugated
Platform ID
BAB288051078
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
NameFZD7 Rabbit pAb- ABclonal
Cat. No.A4213
Accession NumberO75084
Gene ID (Entrez)8324
RRIDAB_2765562
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight70-72kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Synonyms
FzE3; FZD7
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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