Fas Ligand antibody,Genetex,GTX66619

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB420366387

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFas Ligand antibody
Cat. No.GTX66619
Gene ID (Entrez)356
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFASLG
ImmunogenSynthetic peptide, corresponding to amino acids 100-150 of Human FasL.
PurityPurified by antigen-affinity chromatographyFrom serum
Appearance/FormLiquid
FormulationPBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]

Synonyms

Fas ligand , ALPS1B , APT1LG1 , APTL , CD178 , CD95-L , CD95L , FASL , TNFSF6 , TNLG1A

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