Fascin 1 antibody,Genetex,GTX55616

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB510045849

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFascin 1 antibody
Cat. No.GTX55616
Gene ID (Entrez)6624
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetFSCN1
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human FSCN1 (NP_003079.1).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Synonyms

fascin actin-bundling protein 1 , FAN1 , HSN , SNL , p55

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