Fascin 1 antibody [HL5768],Genetex,GTX646839

Host

Rabbit

Reactivity

Human, Mouse

Application

WB

Conjugate

Unconjugated

Platform ID

BAB913419723

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFascin 1 antibody [HL5768]
Cat. No.GTX646839
Gene ID (Entrez)6624
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentrationbatch dependent (Please refer to the vial label for the specific concentration.)
TargetFSCN1
ImmunogenRecombinant fragment of human Fascin 1.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Synonyms

fascin actin-bundling protein 1 , FAN1 , HSN , SNL , p55

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