Fatty Acid Synthase (FASN) Rabbit mAb,ABclonal,A19050

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB531890301

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameFatty Acid Synthase (FASN) Rabbit mAb
Cat. No.A19050
Accession NumberP49327
Gene ID (Entrez)2194
RRIDAB_2862543
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, IP, ELISA
Working DilutionsWB:1:1000 - 1:2000 | IHC-P:1:500 - 1:2000 | IF/ICC:1:100 - 1:800 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0377
Molecular Weight273kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Synonyms

FAS; OA-519; SDR27X1; Fatty Acid Synthase (FASN)

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