Fibrinogen gamma antibody [5A6],Genetex,GTX60498

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB078374300

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFibrinogen gamma antibody [5A6]
Cat. No.GTX60498
Gene ID (Entrez)2266
HostMouse
IsotypeIgG2b
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityMonoclonal
TargetFGG
ImmunogenPurified recombinant fragment of human FGG(AA : 210 - 437) expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Synonyms

fibrinogen gamma chain

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