Fibroblast activation protein-α (FAP) Rabbit mAb,ABclonal,A23789

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB912774975

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameFibroblast activation protein-α (FAP) Rabbit mAb
Cat. No.A23789
Accession NumberQ12884
Gene ID (Entrez)2191
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:1000 - 1:4000 | IF/ICC:1:200 - 1:800 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC61700
Molecular Weight95kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

FAP; DPPIV; FAPA; FAPalpha; SIMP; prolyl endopeptidase FAP; Fibroblast activation protein-α (FAP)

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