Fibronectin/FN1 Polyclonal Antibody, FITC Conjugated,Bioss,bs-0666R-FITC

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow

Application

WB, IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

FITC

Platform ID

BAB539251593

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFibronectin/FN1 Polyclonal Antibody, FITC Conjugated
Cat. No.bs-0666R-FITC
Accession NumberP11276
Gene ID (Entrez)14268
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Cow
ConjugationFITC
ApplicationWB, IF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsWB:1:300-5000 | IF(IHC-P):1:50-200 | IF(IHC-F):1:50-200 | IF(ICC):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).

Synonyms

Fn; Fn-1; E3327I9; Fibronectin; Fn1

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