Filaggrin antibody [FLG01],Genetex,GTX23137

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF IHC-P IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB926635905

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFilaggrin antibody [FLG01]
Cat. No.GTX23137
Gene ID (Entrez)2312
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFLG
ImmunogenRecombinant full length protein
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS, 0.2% BSA,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]

Synonyms

filaggrin , ATOD2

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