Flt3 Ligand antibody [9G23],Genetex,GTX52748

Host

Mouse

Reactivity

Human

Application

WB Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB435070590

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFlt3 Ligand antibody [9G23]
Cat. No.GTX52748
Gene ID (Entrez)2323
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB Neutralizing /Inhibition
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetFLT3LG
ImmunogenHuman recombinant Flt-3 ligand
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

Synonyms

FL , FLT3L , FLT3LG , fms related tyrosine kinase 3 ligand , Flt3-L , FLT3 ligand

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