Frizzled 8 antibody,Genetex,GTX71543

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB923414923

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameFrizzled 8 antibody
Cat. No.GTX71543
Gene ID (Entrez)8325
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Monkey
ConjugationUnconjugated
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetFZD8
ImmunogenSynthetic 15 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Synonyms

frizzled class receptor 8 , FZ8 , FZD8 , hFZ8 , frizzled8

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