GAB1 Recombinant Antibody,Bioss,bsm-54220r

Host

Rabbit

Application

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB917526256

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameGAB1 Recombinant Antibody
Cat. No.bsm-54220r
Accession NumberQ13480
Gene ID (Entrez)2549
HostRabbit
IsotypeIgG
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:300-5000 | FCM:1:20-100 | IHC-P:1:200-400 | IF(IHC-P):1:50-200 | IF(ICC):1:50-200
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageStore at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Scientific Background

GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway.

Synonyms

GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1; GAB1.

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