GAD65 + GAD67 Polyclonal Antibody,Bioss,bs-13263R

Host

Rabbit

Reactivity

Human, Mouse

Application

WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB733392154

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGAD65 + GAD67 Polyclonal Antibody
Cat. No.bs-13263R
Accession NumberQ05329, Q99259
Gene ID (Entrez)25722571
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF(IHC-P):1:50-200 | IF(IHC-F):1:50-200 | IF(ICC):1:50-200
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.

Synonyms

Glutamate decarboxylase 2; GAD2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase 1; GAD1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform

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