GAPDH Loading Control Antibody, Mouse Mab,Sino Biological,100242-MM05

Monoclonal Mouse IgG1 Clone #05

Host

Mouse

Reactivity

Human

Application

WB; IHC-P

Conjugate

Unconjugated

Platform ID

BAB172792405

Sino Biological

Headquarters

Building 9, Yard 18, Kechuang 10th Street, Beijing Economic-Technological Development Area, Daxing District, Beijing 100176, China

Sino Biological

Contact

Tel: 400-890-9989
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGAPDH Loading Control Antibody, Mouse Mab
Cat. No.100242-MM05
HostMouse
RRIDAB_2860062
ReactivityHuman
ConjugationUnconjugated
ApplicationWB; IHC-P
Working DilutionsWB:1:500-1:2000; IHC-P:1:100-1:500
ImmunogenA synthetic peptide corresponding to the center region of the human GAPDH
PurityProtein A
Appearance/FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Formulation0.2 μm filtered solution in PBS
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Scientific Background

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.

Synonyms

Anti-CDABP0047 Antibody; Anti-G3PD Antibody; Anti-GAPD Antibody; Anti-HEL-S-162eP Antibody; Anti-OK/SW-cl.12 Antibody; glyceraldehyde-3-phosphate dehydrogenase

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