GFAP Antibody (YA416),MedChemexpress,HY-P80140

GFAP Antibody (YA416) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GFAP.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,IHC-F,ICC/IF,IP,IF-Tissue,mIHC

Conjugate

Non-conjugated

Platform ID

BAB066672794

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Verification Image
Scientific Background

Specifications

NameGFAP Antibody (YA416)
Cat. No.HY-P80140
Accession NumberP14136
Gene ID (Entrez)2670
HostRabbit
RRIDAB_3102091
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,IHC-F,ICC/IF,IP,IF-Tissue,mIHC
Working DilutionsWB: 1:1000-1:5000; IHC-P: 1:100-1:1000; IHC-F: 1:200-1:500; IF-Tissue: 1:200-1:500; ICC/IF: 1:50-1:200; mIHC: 1:1000-1:10000; IP: Use at an assay dependent concentration.
ClonalityRecombinant,Monoclonal
Clone NumberYA416
Molecular WeightPredicted band size: 50 kDa; Observed band size: 50 kDa
ImmunogenSynthetic peptide corresponding to Human GFAP.AA range:1-50.
PurityProtein A affinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

Glial Fibrillary Acidic Protein (GFAP), classified as a class-III intermediate filament, functions as a cell-specific marker crucial for distinguishing astrocytes from other glial cells, particularly during the development of the central nervous system. GFAP plays a pivotal role in the formation and maintenance of the cytoskeleton in astrocytes, contributing to their structural support and stability. Its expression is highly specific to astrocytes, making it a valuable marker in identifying these glial cells in various physiological and pathological contexts. Furthermore, GFAP has been reported to interact with SYNM, suggesting potential functional associations with proteins involved in cytoskeletal dynamics or cellular signaling pathways within astrocytes. This interaction adds a layer of complexity to the understanding of GFAP's role in astrocyte biology. Ongoing research may reveal additional details about the molecular mechanisms and functional implications of GFAP in the central nervous system.

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