GLP1R antibody [HL2297],Genetex,GTX638352

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB338694344

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGLP1R antibody [HL2297]
Cat. No.GTX638352
Gene ID (Entrez)2740
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationIHC-P
ClonalityMonoclonal
Concentration2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetGLP1R
ImmunogenSynthetic peptide encompassing a sequence within the Extracellular domain human of GLP1R. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

Synonyms

glucagon like peptide 1 receptor , GLP-1 , GLP-1-R , GLP-1R

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