GMP Pacific Blue™ anti-human CD7 Antibody, CD7, CD7-6B7,BioLegend,260298

Additional reported (for the relevant formats) applications include proteogenomics2.

Host

Mouse

Application

FC - Quality tested

Platform ID

BAB278966705

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameGMP Pacific Blue™ anti-human CD7 Antibody, CD7, CD7-6B7
Cat. No.260298
HostMouse
IsotypeMouse IgG2a, κ
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberCD7-6B7
Concentration100 µg/mL
TargetCD7
ImmunogenKG1a cell line
PurityThe antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA) and a stabilizer
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

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