GMP Ultra-LEAF™ Biotin anti-human HLA-A,B,C SF Antibody, HLA-ABC, W6/32,BioLegend,311457
Clone W6/32 recognizes residues in the N terminus of the human ß2-microglobulin molecule21.Additional reported applications (for the relevant formats) include: immunoprecipitaton2, Western blotting (non-reducing)3, immunohistochemical staining of acetone-fixed frozen tissue sections4,5, blocking6,7, inhibition of NK cell-mediated lysis10, and activation8,9. Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections17.
Host
Mouse
Application
FC - Quality testedActiv, Block, IHC-F, IP, WB - Reported in the literature, not verified in house
Platform ID
BAB905278575
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameGMP Ultra-LEAF™ Biotin anti-human HLA-A,B,C SF Antibody, HLA-ABC, W6/32
Cat. No.311457
HostMouse
IsotypeMouse IgG2a, κ
ApplicationFC - Quality testedActiv, Block, IHC-F, IP, WB - Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberW6/32
Concentration1.0 mg/mL
TargetHLA-A
PurityThe Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Formulation0.1 μm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/μg of the protein (< 0.001 ng/μg of the protein) as determined by the LAL test
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only
Scientific Background
MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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