GPS2 antibody [HL2276],Genetex,GTX638329

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB213631874

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGPS2 antibody [HL2276]
Cat. No.GTX638329
Gene ID (Entrez)2874
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Zebrafish
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityMonoclonal
Concentration2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetGPS2
ImmunogenRecombinant fragmemt of human GPS2.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]

Synonyms

G protein pathway suppressor 2 , AMF-1

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