GSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody,Genetex,GTX132997

Host

Rabbit

Reactivity

Human, Mouse

Application

WB IHC-Fr

Conjugate

Unconjugated

Platform ID

BAB220451128

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameGSK3 alpha (phospho Ser21) + GSK3 beta (phospho Ser9) antibody
Cat. No.GTX132997
Gene ID (Entrez)2932
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IHC-Fr
ClonalityPolyclonal
Concentration0.13 mg/ml (Please refer to the vial label for the specific concentration.)
TargetGSK3B
ImmunogenCarrier-protein conjugated synthetic peptide surrounding phospho Ser9 of human GSK3 beta. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase (see GYS1, MIM 138570). Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM]

Synonyms

glycogen synthase kinase 3 beta

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