Galectin 8 Recombinant Antibody,Bioss,bsm-54301r-100ul

Host

Rabbit

Reactivity

Human

Application

Flow-Cyt, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB355094973

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGalectin 8 Recombinant Antibody
Cat. No.bsm-54301r-100ul
Accession NumberO00214
Gene ID (Entrez)3964
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationFlow-Cyt, ICC/IF
Working DilutionsFlow-Cyt:1:50-100 | ICC/IF:1:50-200
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.

Synonyms

Galectin-8; Po66 carbohydrate-binding protein; Prostate carcinoma tumor antigen 1; Gal-8; Po66-CBP; PCTA-1; LGALS8

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