Glutaminase (GLS) Rabbit mAb,ABclonal,A23189

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB472907362

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Product Specifications
Scientific Background
Synonyms

Specifications

NameGlutaminase (GLS) Rabbit mAb
Cat. No.A23189
Accession NumberO94925
Gene ID (Entrez)2744
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IF/ICC:1:50 - 1:200 | IF-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC59924
Molecular Weight55-65 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

Synonyms

GAC; GAM; KGA; GLS1; AAD20; DEE71; GDPAG; CASGID; EIEE71; Glutaminase (GLS)

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