Glutathione Reductase antibody [N2C2], Internal,Genetex,GTX114199

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P EM

Conjugate

Unconjugated

Platform ID

BAB820075814

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGlutathione Reductase antibody [N2C2], Internal
Cat. No.GTX114199
Gene ID (Entrez)2936
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P EM
ClonalityPolyclonal
Concentration1.21 mg/ml (Please refer to the vial label for the specific concentration.)
TargetGSR
ImmunogenRecombinant protein encompassing a sequence within the center region of human Glutathione Reductase. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq]

Synonyms

glutathione-disulfide reductase , GR , HEL-75 , HEL-S-122m

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