Glycophorin C antibody [Ret40f],Genetex,GTX29521

Host

Mouse

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB934632065

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameGlycophorin C antibody [Ret40f]
Cat. No.GTX29521
Gene ID (Entrez)2995
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityMonoclonal
TargetGYPC
ImmunogenBALB/C mice were injected with red cell ghosts.
PurityUnpurified
Appearance/FormLiquid
FormulationTissue culture supernatant,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Synonyms

glycophorin C (Gerbich blood group) , CD236 , CD236R , GE , GE:GPC:GPD:GYPD , GPC , GPD , GYPD , PAS-2 , PAS-2'

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