Granzyme B antibody [GB10] (Biotin),Genetex,GTX75842

Host

Mouse

Reactivity

Human, Chimpanzee

Application

ELISA

Conjugate

Biotin

Platform ID

BAB926713339

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameGranzyme B antibody [GB10] (Biotin)
Cat. No.GTX75842
Gene ID (Entrez)3002
HostMouse
IsotypeIgG1
ReactivityHuman, Chimpanzee
ConjugationBiotin
ApplicationELISA
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetGZMB
ImmunogenPurified human Granzyme B.
PurityProtein A purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationTBS, 1% BSA,0.001% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Synonyms

granzyme B , C11 , CCPI , CGL-1 , CGL1 , CSP-B , CSPB , CTLA1 , CTSGL1 , HLP , SECT

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