Gremlin 1 antibody,Genetex,GTX03707

Host

Rabbit

Reactivity

Human, Mouse

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB598448453

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameGremlin 1 antibody
Cat. No.GTX03707
Gene ID (Entrez)23892
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetGrem1
ImmunogenKLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.
PurityProtein A purified followed by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.09% sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Enables receptor ligand activity; transmembrane receptor protein tyrosine kinase activator activity; and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; nephron epithelium morphogenesis; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of branching involved in ureteric bud morphogenesis; and regulation of signal transduction. Located in extracellular space. Colocalizes with cell surface. Is expressed in several structures, including embryo mesenchyme; limb bud; neural ectoderm; sensory organ; and skeleton. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]

Synonyms

gremlin 1, DAN family BMP antagonist , Cktsf1b1 , Drm , Grem , ld

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