HCF1 antibody [N1], N-term,Genetex,GTX114922

Host

Rabbit

Reactivity

Human, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB134581101

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameHCF1 antibody [N1], N-term
Cat. No.GTX114922
Gene ID (Entrez)3054
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.76 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHCFC1
ImmunogenRecombinant protein encompassing a sequence within the center region of human HCF1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq]

Synonyms

host cell factor C1 , CFF , HCF , HCF-1 , HCF1 , HFC1 , MRX3 , PPP1R89 , VCAF

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