HCN4 antibody,Genetex,GTX54825

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-Fr IP

Conjugate

Unconjugated

Platform ID

BAB944216198

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHCN4 antibody
Cat. No.GTX54825
Gene ID (Entrez)10021
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-Fr IP
ClonalityPolyclonal
Concentration0.8 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHCN4
ImmunogenGST fusion protein with sequence HGHLHDSAEERRLIAEGDASPG EDRTPPGLAAEPERP, corresponding to amino acid residues 119-155 (Intracellular, N-terminus) of human HCN4 (Accession : Q9Y3Q4), (MW: 31 kDa.).
PurityDepleted of anti-GST antibodies by affinity chromatography on immobilized GST and purified by antigen-affinity chromatography.From serum
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]

Synonyms

hyperpolarization activated cyclic nucleotide gated potassium channel 4 , SSS2

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