HDAC1 Rabbit mAb,ABclonal,A19571

Reactivity

Human, Mouse, Rat

Application

IHC-P, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB975056330

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameHDAC1 Rabbit mAb
Cat. No.A19571
Accession NumberQ13547
Gene ID (Entrez)3065
RRIDAB_2862675
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationIHC-P, IF/ICC, ELISA
Working DilutionsIHC-P:1:500 - 1:2000 | IF/ICC:1:100 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC0050
Molecular WeightRefer to figures
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Synonyms

HD1; RPD3; KDAC1; GON-10; RPD3L1; C1

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