HDAC3 antibody [7G6C5],Genetex,GTX83173

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB379574712

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHDAC3 antibody [7G6C5]
Cat. No.GTX83173
Gene ID (Entrez)8841
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityMonoclonal
TargetHDAC3
ImmunogenPurified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

Synonyms

histone deacetylase 3 , HD3 , KDAC3 , RPD3 , RPD3-2

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