HDAC4 antibody [N3C1], Internal,Genetex,GTX110231

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P IHC-Fr IP

Conjugate

Unconjugated

Platform ID

BAB000023191

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHDAC4 antibody [N3C1], Internal
Cat. No.GTX110231
Gene ID (Entrez)9759
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr IP
ClonalityPolyclonal
Concentration1.72 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHDAC4
ImmunogenRecombinant protein encompassing a sequence within the center region of human HDAC4. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq]

Synonyms

histone deacetylase 4 , AHO3 , BDMR , HA6116 , HD4 , HDAC-4 , HDAC-A , HDACA

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