HDAC6 antibody [4C5],Genetex,GTX84377

Host

Mouse

Reactivity

Human, Mouse, Rat, Dog, Monkey

Application

WB ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB008385382

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameHDAC6 antibody [4C5]
Cat. No.GTX84377
Gene ID (Entrez)10013
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Dog, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM
ClonalityMonoclonal
Concentration0.84 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHDAC6
ImmunogenFull length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

Synonyms

histone deacetylase 6 , CPBHM , HD6 , JM21 , PPP1R90

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