HDAC8 Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-52088r-bf680-100ul

Host

Rabbit

Reactivity

Human

Application

WB

Conjugate

AbBy Fluor-680

Platform ID

BAB084479873

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameHDAC8 Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-52088r-bf680-100ul
Accession NumberQ9BY41
Gene ID (Entrez)55869
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationAbBy Fluor-680
ApplicationWB
Working DilutionsWB:1:300-5000
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Synonyms

HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1; Histone deacetylase 8; HDAC8

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