HDAC9 Antibody (YA2967),MedChemexpress,HY-P83222

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by The related gene has sequence homology to members of the histone deacetylase family. The related gene is orthologous to the Xenopus and mouse MITR related genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. The encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for The related gene but the full-length nature of some of them has not been determined.

Histone deacetylase 9; HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription repressor MITR; HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR