HEY1 polyclonal antibody,Bioss,bs-16500R

Host

Rabbit

Application

WB, ELISA, IHC-P, IHC-F, IF

Conjugate

Unconjugated

Platform ID

BAB298222285

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background

Specifications

NameHEY1 polyclonal antibody
Cat. No.bs-16500R
Accession NumberQ9Y5J3
Gene ID (Entrez)23462
HostRabbit
IsotypeIgG
ConjugationUnconjugated
ApplicationWB, ELISA, IHC-P, IHC-F, IF
Working DilutionsWB: | ELISA:1:500-1000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF:1:100-500
ClonalityPolyclonal
Concentration1mg/ml
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated inneurogenesisand somitogenesis. Alternative splicing results in multiple transcript variantsbe required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

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