HIF1AN antibody,Genetex,GTX30646
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application
WB ICC/IF IHC-P IHC-Fr IP EM IHC
Conjugate
Unconjugated
Platform ID
BAB685806501
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameHIF1AN antibody
Cat. No.GTX30646
Gene ID (Entrez)55662
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr IP EM IHC
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHIF1AN
ImmunogenA synthetic peptide made to the C-terminal region of human Factor Inhibiting HIF-1 (between residues 300 and the C-terminus). [UniProt# Q9NWT6]
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationTris-Citrate/Phosphate,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only
Scientific Background
Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
Synonyms
hypoxia inducible factor 1 subunit alpha inhibitor , FIH1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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