HIF2 alpha antibody,Genetex,GTX30114

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey, Fish

Application

WB ICC/IF IHC-P IHC

Conjugate

Unconjugated

Platform ID

BAB310319235

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHIF2 alpha antibody
Cat. No.GTX30114
Gene ID (Entrez)13819
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Monkey, Fish
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetEpas1
ImmunogenA peptide derived from the mouse/human HIF2 alpha.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells. (1)

Synonyms

endothelial PAS domain protein 1 , HIF-2alpha , HIF2A , HLF , HRF , MOP2 , bHLHe73

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