HLA-G antibody [MEM-G/1],Genetex,GTX75708

Host

Mouse

Reactivity

Human

Application

WB IHC

Conjugate

Unconjugated

Platform ID

BAB551525929

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameHLA-G antibody [MEM-G/1]
Cat. No.GTX75708
Gene ID (Entrez)3135
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHLA-G
ImmunogenDenaturated heavy chain full-length recombinant human HLA-G
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Synonyms

HLAG , MHCG , major histocompatibility complex, class I, G , HLA-G

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