HMGB1 antibody,Genetex,GTX112959

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish

Application

WB ICC/IF IHC-P IHC-Wm

Conjugate

Unconjugated

Platform ID

BAB442289652

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHMGB1 antibody
Cat. No.GTX112959
Gene ID (Entrez)3146
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Zebrafish
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Wm
ClonalityPolyclonal
Concentration0.53 mg/ml (Please refer to the vial label for the specific concentration.)
TargetHMGB1
ImmunogenRecombinant protein encompassing a sequence within the center region of human HMGB1. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 10% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.

Synonyms

high mobility group box 1 , HMG-1 , HMG1 , HMG3 , SBP-1

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