HMGB2 Rabbit mAb,ABclonal,A9168

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IF/ICC, IP, ELISA, ChIP, CUT&Tag

Conjugate

Unconjugated

Platform ID

BAB094921296

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHMGB2 Rabbit mAb
Cat. No.A9168
Accession NumberP26583
Gene ID (Entrez)3148
RRIDAB_2863677
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, IP, ELISA, ChIP, CUT&Tag
Working DilutionsWB:1:1000 - 1:6000 | IHC-P:1:200 - 1:2000 | IF/ICC:1:100 - 1:1000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. | ChIP:5μg antibody for 10μg-15μg of Chromatin | CUT&Tag:10⁵ cells /1 μg
Clone NumberARC1460
Molecular Weight24 kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Synonyms

HMG2; HMGB2

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