HP1 alpha Recombinant Antibody,Bioss,bsm-61202r-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC), IP

Conjugate

Unconjugated

Platform ID

BAB112666337

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameHP1 alpha Recombinant Antibody
Cat. No.bsm-61202r-100ul
Accession NumberP45973
Gene ID (Entrez)23468
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC), IP
Working DilutionsWB:1:500-2000 | FCM:FCM1μg/Test | IHC-P:IHC-P1:100-500 | IHC-F:IHC-F1:100-500 | IF(IHC-P):IFIHC-P1:100-500 | IF(ICC):IFICC1:50-200 | IP:IP1:20-50
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Synonyms

CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha.

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