HRP Anti-Bid antibody [Y8],Abcam,AB201754

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Human, Human

Application

WB, IHC-P

Conjugate

HRP

Platform ID

BAB338281898

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameHRP Anti-Bid antibody [Y8]
Cat. No.AB201754
HostRabbit
IsotypeIgG
ReactivityHuman, Human
ConjugationHRP
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberY8
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Proclin 300 Solution Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Induces caspases and apoptosis (PubMed : 14583606). Counters the protective effect of BCL2 (By similarity).. BH3-interacting domain death agonist p15. Induces caspase activation and apoptosis (PubMed : 15661737, PubMed : 32029622). Translocates to mitochondria following cleavage and disrupts the outer mitochondrial membrane leading to the release of cytochrome c (PubMed : 10480954, PubMed : 32029622, PubMed : 9727491).. Isoform 1. Induces ICE-like proteases and apoptosis.. Isoform 2. Induces ICE-like proteases and apoptosis.. Isoform 3. Does not induce apoptosis.. Isoform 4. Induces ICE-like proteases and apoptosis. See full target information BID

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