HRP Anti-CTLA4 antibody [KT50],Abcam,AB106490

Host

Mouse

Reactivity

Human

Application

sELISA

Conjugate

HRP

Platform ID

BAB401662725

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameHRP Anti-CTLA4 antibody [KT50]
Cat. No.AB106490
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationHRP
ApplicationsELISA
ClonalityMonoclonal
Clone NumberKT50
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CTLA4.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Thimerosal (merthiolate) Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Inhibitory receptor acting as a major negative regulator of T-cell responses (PubMed : 11279501, PubMed : 11279502, PubMed : 16551244, PubMed : 1714933, PubMed : 18641304, PubMed : 28484017). Acts as a decoy receptor : the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28 (PubMed : 11279501, PubMed : 11279502, PubMed : 16551244, PubMed : 1714933, PubMed : 28484017). See full target information CTLA4

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