HRP Anti-Histone H2B antibody [mAbcam 52484],Abcam,AB204463

Host

Mouse

Reactivity

Human

Application

IHC-P, WB

Conjugate

HRP

Platform ID

BAB277799679

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameHRP Anti-Histone H2B antibody [mAbcam 52484]
Cat. No.AB204463
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationHRP
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumbermAbcam 52484
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Proclin 300 Solution Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. See full target information H2BC12 Additional targets ,H2BC17,H2BC13,H2BC18,H2BC21 acetyl K15,,,H2BC11,H2BC4,,,H2BC3,H2BC12L

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