HRP Anti-Mitofusin 1 antibody [11E91H12],Abcam,AB198410

Target data Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed : 12527753, PubMed : 15297672, PubMed : 23921378, PubMed : 24513856). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed : 15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed : 12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity). See full target information Mfn1