HRP Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] - Plasma Membrane Loading Control,Abcam,AB196696

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

WB, IHC-P

Conjugate

HRP

Platform ID

BAB525325867

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameHRP Anti-alpha 1 Sodium Potassium ATPase antibody [464.6] - Plasma Membrane Loading Control
Cat. No.AB196696
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Human
ConjugationHRP
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone Number464.6
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.1% Proclin 300 Solution Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients (PubMed : 29499166, PubMed : 30388404). Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis (By similarity). See full target information ATP1A1

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