HRP-conjugated Digoxin Rabbit mAb,ABclonal,A24114
Reactivity
Species independent
Application
DB, ELISA
Conjugate
HRP
Platform ID
BAB295758641
ABclonal
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Product Specifications
Scientific Background
Synonyms
Specifications
NameHRP-conjugated Digoxin Rabbit mAb
Cat. No.A24114
IsotypeIgG
ReactivitySpecies independent
ConjugationHRP
ApplicationDB, ELISA
Working DilutionsDB:1:500 - 1:3000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC50289
Molecular WeightRefer to figures
ImmunogenChemical compounds corresponding to Digoxin.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c, caspases 8 and 3.
Synonyms
Digoxin; HRP-conjugated Digoxin
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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